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Acepromazine

Grade

Multimodal Anaesthesia | [KAX]

Therapeutics

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Evidence

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Acepromazine Literature Review

  1. Cruz, F.S., Carregaro, A.B., Raiser, A.G., Zimmerman, M., Lukarsewski, R., Steffen, R.P., 2010. Total intravenous anesthesia with propofol and S(+)-ketamine in rabbits. Vet Anaesth Analg 37, 116–122. https://doi.org/10.1111/j.1467-2995.2009.00513.x

  2. Donovan, J., Brown, P., 2001. Anesthesia. Curr Protoc Immunol Chapter 1, Unit 1.4. https://doi.org/10.1002/0471142735.im0104s27

  3. Ghaffari, M.S., Moghaddassi, A.P., 2010. Effects of ketamine-diazepam and ketamine-acepromazine combinations on intraocular pressure in rabbits. Vet Anaesth Analg 37, 269–272. https://doi.org/10.1111/j.1467-2995.2010.00531.x

  4. Ghaffari, M.S., Moghaddassi, A.P., Bokaie, S., 2009. Effects of intramuscular acepromazine and diazepam on tear production in rabbits. Vet Rec 164, 147–148. https://doi.org/10.1136/vr.164.5.147

  5. Hobbs, B.A., Rolhall, T.G., Sprenkel, T.L., Anthony, K.L., 1991. Comparison of several combinations for anesthesia in rabbits. Am J Vet Res 52, 669–674.

  6. Jeske, J., Stochla, K., 1966. [Effect of acetylpromazine on blood sugar as well as on hypoglycemia and hyperglycemia in rabbits]. Acta Pol Pharm 23, 285–287.

  7. Lefebvre, H.P., Jaeg, J.P., Rico, A.G., Toutain, P.L., Braun, J.P., 1992. Variations of plasma creatine kinase in rabbits following repetitive blood sampling effects of pretreatment with acepromazine, carazolol and dantrolene. Eur J Clin Chem Clin Biochem 30, 425–428.

  8. Lipman, N.S., Marini, R.P., Erdman, S.E., 1990. A comparison of ketamine/xylazine and ketamine/xylazine/acepromazine anesthesia in the rabbit. Lab Anim Sci 40, 395–398.

  9. Ludders, J.W., Thomas, C.B., Sharp, P., Sedgwick, C.J., 1987. An anesthetic technique for repeated collection of blood from New Zealand White rabbits. Laboratory animal science (USA).

  10. Mazzaferro, V., Makowka, L., Enrichens, F., Kahn, D., Ferla, G., Banner, B., Olivero, G., Selby, R.R., Stevenson, W.C., Todo, S., 1989. A modified technique of orthotopic transplant of the kidney in rabbits. J Invest Surg 2, 293–303. https://doi.org/10.3109/08941938909057435

  11. McCormick, M.J., Ashworth, M.A., 1971. Acepromazine and methoxyflurane anesthesia of immature New Zealand white rabbits. Lab Anim Sci 21, 220–223.

  12. Moore, L.R., Chang, S.F., Greenstein, E.T., 1987. Urethane-acepromazine: a novel method of administering parenteral anesthesia in the rabbit. Methods Find Exp Clin Pharmacol 9, 711–715.

  13. Najman, I.E., Ferreira, J.Z., Abimussi, C.J.X., Floriano, B.P., Meneghetti, T.M., Oliva, V.N.L.S., do Nascimento, P., 2015. Ultrasound-assisted periconal ocular blockade in rabbits. Vet Anaesth Analg 42, 433–441. https://doi.org/10.1111/vaa.12237

  14. Raillard, M., Detotto, C., Grepper, S., Beslac, O., Fujioka-Kobayashi, M., Schaller, B., Saulacic, N., 2019. Anaesthetic and Perioperative Management of 14 Male New Zealand White Rabbits for Calvarial Bone Surgery. Animals (Basel) 9, 896. https://doi.org/10.3390/ani9110896

  15. Vachon, P., 1999. Self-mutilation in rabbits following intramuscular ketamine-xylazine-acepromazine injections. Can Vet J 40, 581–582.

Premedication

  1. Cruz, F.S., Carregaro, A.B., Raiser, A.G., Zimmerman, M., Lukarsewski, R., Steffen, R.P., 2010. Total intravenous anesthesia with propofol and S(+)-ketamine in rabbits. Vet Anaesth Analg 37, 116–122. https://doi.org/10.1111/j.1467-2995.2009.00513.x

  2. McCormick, M.J., Ashworth, M.A., 1971. Acepromazine and methoxyflurane anesthesia of immature New Zealand white rabbits. Lab Anim Sci 21, 220–223.

KAX Anaesthesia

  1. Donovan, J., Brown, P., 2001. Anesthesia. Curr Protoc Immunol Chapter 1, Unit 1.4. https://doi.org/10.1002/0471142735.im0104s27

  2. Ghaffari, M.S., Moghaddassi, A.P., 2010. Effects of ketamine-diazepam and ketamine-acepromazine combinations on intraocular pressure in rabbits. Vet Anaesth Analg 37, 269–272. https://doi.org/10.1111/j.1467-2995.2010.00531.x

  3. Hobbs, B.A., Rolhall, T.G., Sprenkel, T.L., Anthony, K.L., 1991. Comparison of several combinations for anesthesia in rabbits. Am J Vet Res 52, 669–674.

  4. Lipman, N.S., Marini, R.P., Erdman, S.E., 1990. A comparison of ketamine/xylazine and ketamine/xylazine/acepromazine anesthesia in the rabbit. Lab Anim Sci 40, 395–398.

  5. Ludders, J.W., Thomas, C.B., Sharp, P., Sedgwick, C.J., 1987. An anesthetic technique for repeated collection of blood from New Zealand White rabbits. Laboratory animal science (USA).

  6. Mazzaferro, V., Makowka, L., Enrichens, F., Kahn, D., Ferla, G., Banner, B., Olivero, G., Selby, R.R., Stevenson, W.C., Todo, S., 1989. A modified technique of orthotopic transplant of the kidney in rabbits. J Invest Surg 2, 293–303. https://doi.org/10.3109/08941938909057435

  7. Najman, I.E., Ferreira, J.Z., Abimussi, C.J.X., Floriano, B.P., Meneghetti, T.M., Oliva, V.N.L.S., do Nascimento, P., 2015. Ultrasound-assisted periconal ocular blockade in rabbits. Vet Anaesth Analg 42, 433–441. https://doi.org/10.1111/vaa.12237

  8. Raillard, M., Detotto, C., Grepper, S., Beslac, O., Fujioka-Kobayashi, M., Schaller, B., Saulacic, N., 2019. Anaesthetic and Perioperative Management of 14 Male New Zealand White Rabbits for Calvarial Bone Surgery. Animals (Basel) 9, 896. https://doi.org/10.3390/ani9110896

Expert Opinion

  1. 1317822 Extrapolation of pharmacological properties in man and veterinary species. Some material employed in collating the data displayed here was taken from veterinary product datasheets or extrapolated from pharmacology texts.



Monograph Details

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