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Enrofloxacin

Grade

Sensitive Infections

Therapeutics

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Evidence

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  1. Agnoletti, F., Brunetta, R., Bano, L., Drigo, I., Mazzolini, E., 2018. Longitudinal study on antimicrobial consumption and resistance in rabbit farming. Int J Antimicrob Agents 51, 197–205. https://doi.org/10.1016/j.ijantimicag.2017.10.007

  2. Aramayona, J.J., Garcia, M.A., Fraile, L.J., Abadía, A.R., Bregante, M.A., 1994. Placental transfer of enrofloxacin and ciprofloxacin in rabbits. Am J Vet Res 55, 1313–1318.

  3. Aramayona, J.J., Mora, J., Fraile, L.J., García, M.A., Abadía, A.R., Bregante, M.A., 1996. Penetration of enrofloxacin and ciprofloxacin into breast milk, and pharmacokinetics of the drugs in lactating rabbits and neonatal offspring. Am J Vet Res 57, 547–553.

  4. Bateman, F.L., Kirejczyk, S.G.M., Stewart, G.V., Cutler, D.C., Quilling, L.L., Howerth, E.W., Mayer, J., 2019. Effects of an enrofloxacin-silver sulfadiazine emulsion in the ears of rabbits with perforated tympanic membranes. Am J Vet Res 80, 325–334. https://doi.org/10.2460/ajvr.80.4.325

  5. Bin, Z., Kai, Z., Jue, Z., Ke, W., Lili, Z., Jian, J., Biao, H., 2013. A novel and sensitive method for the detection of enrofloxacin in food using time-resolved fluoroimmunoassay. Toxicol Mech Methods 23, 323–328. https://doi.org/10.3109/15376516.2012.757685

  6. Blackwell, N.J., 1999. Abscesses in rabbits. Vet Rec 144, 540.

  7. Bregante, M.A., Saez, P., Aramayona, J.J., Fraile, L., Garcia, M.A., Solans, C., 1999. Comparative pharmacokinetics of enrofloxacin in mice, rats, rabbits, sheep, and cows. Am J Vet Res 60, 1111–1116.

  8. Broome, R.L., Brooks, D.L., 1991. Efficacy of enrofloxacin in the treatment of respiratory pasteurellosis in rabbits. Lab Anim Sci 41, 572–576.

  9. Broome, R.L., Brooks, D.L., Babish, J.G., Copeland, D.D., Conzelman, G.M., 1991. Pharmacokinetic properties of enrofloxacin in rabbits. Am J Vet Res 52, 1835–1841.

  10. Cabanes, A., Arboix, M., Garcia Anton, J.M., Reig, F., 1992. Pharmacokinetics of enrofloxacin after intravenous and intramuscular injection in rabbits. Am J Vet Res 53, 2090–2093.

  11. Cabanes, A., Reig, F., Antón, J.M., Arboix, M., 1995. Sustained release of liposome-encapsulated enrofloxacin after intramuscular administration in rabbits. Am J Vet Res 56, 1498–1501.

  12. Elmas, M., Uney, K., Yazar, E., Karabacak, A., Traş, B., 2007. Pharmacokinetics of enrofloxacin following intravenous and intramuscular administration in Angora rabbits. Res Vet Sci 82, 242–245. https://doi.org/10.1016/j.rvsc.2006.06.008

  13. Elmas, M., Yazar, E., Baş, A.L., Traş, B., Bayezit, M., Yapar, K., 2002. Comparative pharmacokinetics of enrofloxacin and tissue concentrations of parent drug and ciprofloxacin after intramuscular administrations of free and liposome-encapsulated enrofloxacin in rabbits. J Vet Med B Infect Dis Vet Public Health 49, 507–512. https://doi.org/10.1046/j.1439-0450.2002.00603.x

  14. Elmas, M., Yazar, E., Uney, K., Er Karabacak, A., Traş, B., 2008. Pharmacokinetics of enrofloxacin and flunixin meglumine and interactions between both drugs after intravenous co-administration in healthy and endotoxaemic rabbits. Vet J 177, 418–424. https://doi.org/10.1016/j.tvjl.2007.05.021

  15. Forcella, C., Alessiani, A., Perilli, M., Zilli, K., Di Giannatale, E., Amicosante, G., 2010. Characterization of quinolone resistance in Escherichia coli strains of animal origin from Italy. J Chemother 22, 165–168. https://doi.org/10.1179/joc.2010.22.3.165

  16. Fraile, L.J., Martinez, C., Aramayona, J.J., Abadía, A.R., Bregante, M.A., García, M.A., 1997. Limited capacity of neonatal rabbits to eliminate enrofloxacin and ciprofloxacin. Vet Q 19, 162–167. https://doi.org/10.1080/01652176.1997.9694764

  17. Gardhouse, S., Sanchez-Migallon Guzman, D., Paul-Murphy, J., Byrne, B.A., Hawkins, M.G., 2017. Bacterial isolates and antimicrobial susceptibilities from odontogenic abscesses in rabbits: 48 cases. Vet Rec 181, 538. https://doi.org/10.1136/vr.103996

  18. Jekl, V., Piskovska, A., Drnkova, I., Skoric, M., Hauptman, K., Chloupek, J., 2021. Case Report: Spontaneous Appendicitis With Suspected Involvement of Klebsiella variicola in Two Pet Rabbits. Front Vet Sci 8, 779517. https://doi.org/10.3389/fvets.2021.779517

  19. Khan, A.M., Rampal, S., Sood, N.K., 2018. Effect of levofloxacin, pazufloxacin, enrofloxacin, and meloxicam on the immunolocalization of ABCG-2 transporter protein in rabbit retina. Environ Sci Pollut Res Int 25, 8853–8860. https://doi.org/10.1007/s11356-018-1216-y

  20. Khan, A.M., Rampal, S., Sood, N.K., 2017. Effect of repeated oral administration of levofloxacin, enrofloxacin, and meloxicam on antioxidant parameters and lipid peroxidation in rabbits. Hum Exp Toxicol 36, 42–50. https://doi.org/10.1177/0960327116637111

  21. Lu, S., Zhang, Y., Liu, J., Zhao, C., Liu, W., Xi, R., 2006. Preparation of anti-pefloxacin antibody and development of an indirect competitive enzyme-linked immunosorbent assay for detection of pefloxacin residue in chicken liver. J Agric Food Chem 54, 6995–7000. https://doi.org/10.1021/jf061309q

  22. Mähler, M., Stünkel, S., Ziegowski, C., Kunstýr, I., 1995. Inefficacy of enrofloxacin in the elimination of Pasteurella multocida in rabbits. Lab Anim 29, 192–199. https://doi.org/10.1258/002367795780740195

  23. Manceau, J., Gicquel, M., Laurentie, M., Sanders, P., 1999. Simultaneous determination of enrofloxacin and ciprofloxacin in animal biological fluids by high-performance liquid chromatography. Application in pharmacokinetic studies in pig and rabbit. J Chromatogr B Biomed Sci Appl 726, 175–184. https://doi.org/10.1016/s0378-4347(99)00026-2

  24. Okewole, E.A., Olubunmi, P.A., 2008. Antibiograms of pathogenic bacteria isolated from laboratory rabbits in Ibadan, Nigeria. Lab Anim 42, 511–514. https://doi.org/10.1258/la.2007.007059

  25. Palócz, O., Gál, J., Clayton, P., Dinya, Z., Somogyi, Z., Juhász, C., Csikó, G., 2014. Alternative treatment of serious and mild Pasteurella multocida infection in New Zealand White rabbits. BMC Vet Res 10, 276. https://doi.org/10.1186/s12917-014-0276-6

  26. Piva, S., Florio, D., Mion, D., Zanoni, R.G., 2016. Antimicrobial Susceptibility of Campylobacter Cuniculorum Isolated from Rabbits Reared in Intensive and Rural Farms. Ital J Food Saf 5, 5829. https://doi.org/10.4081/ijfs.2016.5829

  27. Rougier, S., Galland, D., Boucher, S., Boussarie, D., Vallé, M., 2006. Epidemiology and susceptibility of pathogenic bacteria responsible for upper respiratory tract infections in pet rabbits. Vet Microbiol 115, 192–198. https://doi.org/10.1016/j.vetmic.2006.02.003

  28. Suckow, M.A., Martin, B.J., Bowersock, T.L., Douglas, F.A., 1996. Derivation of Pasteurella multocida-free rabbit litters by enrofloxacin treatment. Vet Microbiol 51, 161–168. https://doi.org/10.1016/0378-1135(96)00022-3

  29. Swennes, A.G., Buckley, E.M., Parry, N.M.A., Madden, C.M., García, A., Morgan, P.B., Astrofsky, K.M., Fox, J.G., 2012. Enzootic enteropathogenic Escherichia coli infection in laboratory rabbits. J Clin Microbiol 50, 2353–2358. https://doi.org/10.1128/JCM.00832-12

  30. Vancraeynest, D., Hermans, K., Martel, A., Vaneechoutte, M., Devriese, L.A., Haesebrouck, F., 2004. Antimicrobial resistance and resistance genes in Staphylococcus aureus strains from rabbits. Vet Microbiol 101, 245–251. https://doi.org/10.1016/j.vetmic.2004.03.021

  31. von Degerfeld, M.M., Banchi, P., Quaranta, G., 2020. Successful Treatment of Pyometra Caused by Pseudomonas aeruginosa Infection in a Rabbit. Top Companion Anim Med 41, 100473. https://doi.org/10.1016/j.tcam.2020.100473

Monograph Details

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