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Doxycycline

Grade

Sensitive Infections

Therapeutics

Evidence

  1. Bastianini, L., Felisati, D., 1970. [Studies on gravidic and fetal toxicity of alpha-6-deoxy-5-oxytetracycline (doxycycline) in mouse and rabbit]. Antibiotica 8, 161–178.

  2. Bilaceroglu, S., Guo, Y., Hawthorne, M.L., Zhu, Z., Stathopoulos, G.T., Lane, K.B., Light, R.W., 2005. Oral forms of tetracycline and doxycycline are effective in producing pleurodesis. Chest 128, 3750–3756. https://doi.org/10.1378/chest.128.5.3750

  3. Clark, W.M., Calcagno, F.A., Gabler, W.L., Smith, J.R., Coull, B.M., 1994. Reduction of central nervous system reperfusion injury in rabbits using doxycycline treatment. Stroke 25, 1411–1415; discussion 1416. https://doi.org/10.1161/01.str.25.7.1411

  4. Gengenbacher, M., Zimmerman, M.D., Sarathy, J.P., Kaya, F., Wang, H., Mina, M., Carter, C., Hossen, M.A., Su, H., Trujillo, C., Ehrt, S., Schnappinger, D., Dartois, V., 2020. Tissue Distribution of Doxycycline in Animal Models of Tuberculosis. Antimicrob Agents Chemother 64, e02479-19. https://doi.org/10.1128/AAC.02479-19

  5. Ghiasian, L., Habibi, A., Aliakbar Navahi, R., Hadavandkhani, A., Akbarian, S., Alemzadeh, S.A., Khorasani, M.A., 2019. Safety of the subconjunctival injection of doxycycline in rabbits. Cutan Ocul Toxicol 38, 390–394. https://doi.org/10.1080/15569527.2019.1641112

  6. Golub, L.M., Lee, H.-M., 2020. Periodontal therapeutics: Current host-modulation agents and future directions. Periodontol 2000 82, 186–204. https://doi.org/10.1111/prd.12315

  7. Lees, G.M., Percy, W.H., 1981. Antibiotic-associated colitis: an in vitro investigation of the effects of antibiotics on intestinal motility. Br J Pharmacol 73, 535–547. https://doi.org/10.1111/j.1476-5381.1981.tb10453.x

  8. Lu, H.-T., Sheu, M.-T., Lin, Y.-F., Lan, J., Chin, Y.-P., Hsieh, M.-S., Cheng, C.-W., Chen, C.-H., 2013. Injectable hyaluronic-acid-doxycycline hydrogel therapy in experimental rabbit osteoarthritis. BMC Vet Res 9, 68. https://doi.org/10.1186/1746-6148-9-68

  9. Mileva, R., Rusenov, A., Milanova, A., 2021. Population Pharmacokinetic Modelling of Orally Administered Doxycycline to Rabbits at Different Ages. Antibiotics (Basel) 10, 310. https://doi.org/10.3390/antibiotics10030310

  10. Miller, Q., Meschter, C., Neumaster, T., Pratt, J., Moulton, M., Downey, D., Harre, J., 2007. Comparison of pleurodesis by erythromycin, talc, doxycycline, and diazepam in a rabbit model. J Surg Educ 64, 41–45. https://doi.org/10.1016/j.cursur.2006.07.006

  11. Perry, H.D., Hodes, L.W., Seedor, J.A., Donnenfeld, E.D., McNamara, T.F., Golub, L.M., 1993. Effect of doxycycline hyclate on corneal epithelial wound healing in the rabbit alkali-burn model. Preliminary observations. Cornea 12, 379–382. https://doi.org/10.1097/00003226-199309000-00002

  12. Salminen, L., 1977. Penetration of ocular compartments by tetracyclines. II. An experimental study with doxycycline. Albrecht Von Graefes Arch Klin Exp Ophthalmol 204, 201–207. https://doi.org/10.1007/BF00414847

  13. Sen, E., Balikoglu-Yilmaz, M., Bozdag-Pehlivan, S., Sungu, N., Aksakal, F.N., Altinok, A., Tuna, T., Unlu, N., Ustun, H., Koklu, G., Öztürk, F., 2010. Effect of doxycycline on postoperative scarring after trabeculectomy in an experimental rabbit model. J Ocul Pharmacol Ther 26, 399–406. https://doi.org/10.1089/jop.2010.0064

  14. Teixeira, L.R., Wu, W., Chang, D.-S., Light, R.W., 2002. The effect of corticosteroids on pleurodesis induced by doxycycline in rabbits. Chest 121, 216–219. https://doi.org/10.1378/chest.121.1.216

  15. Toremalm, N.G., Josefsson, K., Lagergren, I., 1983. Effects of erythromycin, aminoglycosides and doxycycline on mucociliary activity in vitro of rabbit trachea. Pharmacology 26, 40–45. https://doi.org/10.1159/000137767

  16. Wu, W., Teixeira, L.R., Light, R.W., 1998. Doxycycline pleurodesis in rabbits: comparison of results with and without chest tube. Chest 114, 563–568. https://doi.org/10.1378/chest.114.2.563

Monograph Details

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