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Cefotaxime

Grade

Sensitive Infections

Therapeutics

Evidence

  1. Chavanet, P., Champliaud, D., Pechinot, A., Buisson, M., Duong, M., Neuwirth, C., Kazmierczak, A., Portier, H., 1996. In-vivo activity and pharmacodynamics of cefotaxime in combination with vancomycin in fibrin clots infected with highly penicillin-resistant Streptococcus pneumoniae. J Antimicrob Chemother 38, 655–670. https://doi.org/10.1093/jac/38.4.655

  2. Chavanet, P., Muggeo, E., Waldner, A., Dijoux, S., Caillot, D., Portier, H., 1990. Synergism between cefotaxime and fosfomycin in the therapy of methicillin and gentamicin resistant Staphylococcus aureus infection in rabbits. Eur J Clin Microbiol Infect Dis 9, 271–275. https://doi.org/10.1007/BF01968058

  3. Coombes, J.D., 1982. Metabolism of cefotaxime in animals and humans. Rev Infect Dis 4 Suppl, S325-332. https://doi.org/10.1093/clinids/4.supplement_2.s325

  4. Doerr, B.I., Glomot, R., Kief, H., Kramer, M., Sakaguchi, T., 1982. Cefotaxime toxicity studies: a review of preclinical studies and some clinical reports. Rev Infect Dis 4 Suppl, S354-359. https://doi.org/10.1093/clinids/4.supplement_2.s354

  5. Fernandez Vigo, J., Rafart, J., Concheiro, A., Martinez, R., Cordido, M., 1988. Ocular penetration and pharmacokinetics of cefotaxime: an experimental study. Curr Eye Res 7, 1149–1154. https://doi.org/10.3109/02713688809033218

  6. Kazmierczak, A., Pechinot, A., Tremeaux, J.C., Duez, J.M., Kohli, E., Portier, H., 1985. Bactericidal activity of cefotaxime and fosfomycin in cerebrospinal fluid during the treatment of rabbit meningitis experimentally induced by methicillin-resistant Staphylococcus aureus. Infection 13 Suppl 1, S76-80. https://doi.org/10.1007/BF01644224

  7. Luft, F.C., Aronoff, G.R., Evan, A.P., Connors, B.A., Blase, D.K., Gattone, V.H., 1982. Effects of moxalactam and cefotaxime on rabbit renal tissue. Antimicrob Agents Chemother 21, 830–835. https://doi.org/10.1128/AAC.21.5.830

  8. Schaad, U.B., McCracken, G.H., Loock, C.A., Thomas, M.L., 1981. Pharmacokinetics and bacteriologic efficacy of moxalactam, cefotaxime, cefoperazone, and rocephin in experimental bacterial meningitis. J Infect Dis 143, 156–163. https://doi.org/10.1093/infdis/143.2.156

  9. Tago, K., Yabusaki, N., Ueno, A., 1988. Serum and renal tissue concentrations of cefotaxime in urinary tract obstruction in rabbits. Drugs 35 Suppl 2, 65–71. https://doi.org/10.2165/00003495-198800352-00015

Monograph Details

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