Activated Charcoal
Gastrointestinal Decontamination
Gavage: 1-4 g/kg, PO, q4-6h
Dilute into a slurry with 5-10 ml water per g of charcoal
Therapeutics
Evidence Base
Antinoff, N., 1998. Small Mammal Critical Care. Veterinary Clinics of North America: Exotic Animal Practice, Critical Care 1, 153–175. https://doi.org/10.1016/S1094-9194(17)30159-7
Chin, L., Picchioni, A.L., Duplisse, B.R., 1970. The action of activated charcoal on poisons in the digestive tract. Toxicology and Applied Pharmacology 16, 786–799. https://doi.org/10.1016/0041-008X(70)90085-2
DeCubellis, J., 2016. Common Emergencies in Rabbits, Guinea Pigs, and Chinchillas. Veterinary Clinics of North America: Exotic Animal Practice, Emergency and Critical Care 19, 411–429. https://doi.org/10.1016/j.cvex.2016.01.003
Huynh, M., Boyeaux, A., Pignon, C., 2016. Assessment and Care of the Critically Ill Rabbit. Veterinary Clinics of North America: Exotic Animal Practice, Emergency and Critical Care 19, 379–409. https://doi.org/10.1016/j.cvex.2016.01.011
Idid, S.Z., Lee, C.Y., 1996. Effects of Fuller’s Earth and activated charcoal on oral absorption of paraquat in rabbits. Clin Exp Pharmacol Physiol 23, 679–681. https://doi.org/10.1111/j.1440-1681.1996.tb01757.x
Johnston, M.S., 2008. Clinical Toxicoses of Domestic Rabbits. Veterinary Clinics of North America: Exotic Animal Practice, Toxicology 11, 315–326. https://doi.org/10.1016/j.cvex.2007.12.002
Meredith, A.L., Richardson, J., 2015. Neurological Diseases of Rabbits and Rodents. Journal of Exotic Pet Medicine, Neurology 24, 21–33. https://doi.org/10.1053/j.jepm.2014.12.007
Ofoefule, S.I., Onuoha, L.C., Okonta, M.J., Udeogaranya, P.O., Orisakwe, O.E., 2001. Effect of activated charcoal on isoniazid absorption in rabbits. Boll Chim Farm 140, 183–186.
Expert Opinion
McArthur, S., D., J. (2022) | 220719 Extrapolation of pharmacological properties in man and veterinary species. Some material employed in collating the data displayed here was taken from veterinary product datasheets or extrapolated from pharmacology texts.