Aciclovir
Ocular Herpesvirus Infection
Therapeutics
Evidence Base
Collins, P., 1983. The spectrum of antiviral activities of acyclovir in vitro and in vivo. J Antimicrob Chemother 12 Suppl B, 19–27. https://doi.org/10.1093/jac/12.suppl_b.19
Fardeau, C., Langlois, M., Mathys, B., Rafales, P., Nugier, F., Godard, V., Aymard, M., Denis, J., 1991. Emergence of cross-resistant herpes simplex virus following topical drug therapy in rabbit keratitis. Curr Eye Res 10 Suppl, 151–158. https://doi.org/10.3109/02713689109020372
Fardeau, C., Langlois, M., Nugier, F., Asselot, C., Aymard, M., Denis, J., 1993. Cross-resistances to antiviral drugs of IUdR-resistant HSV1 in rabbit keratitis and in vitro. Cornea 12, 19–24. https://doi.org/10.1097/00003226-199301000-00004
Kaufman, H.E., Centifanto-Fitzgerald, Y.M., Varnell, E.D., 1983. Herpes simplex keratitis. Ophthalmology 90, 700–706. https://doi.org/10.1016/s0161-6420(83)34518-8
Maudgal, P.C., Vrijghem, J.C., Molemans, M., Missotten, L., 1985. Effect of topical acyclovir therapy on experimental herpes simplex keratouveitis. Arch Ophthalmol 103, 1389–1392. https://doi.org/10.1001/archopht.1985.01050090141050
Shiota, H., Naito, T., Mimura, Y., 1987. Anti-herpes simplex virus (HSV) effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG) in rabbit cornea. Curr Eye Res 6, 241–245. https://doi.org/10.3109/02713688709020098
Trousdale, M.D., Dunkel, E.C., Nesburn, A.B., 1980. Effect of acyclovir on acute and latent herpes simplex virus infections in the rabbit. Invest Ophthalmol Vis Sci 19, 1336–1341.
Trousdale, M.D., Nesburn, A.B., 1982. Evaluation of the antiherpetic activity of acyclovir in rabbits. Am J Med 73, 155–160. https://doi.org/10.1016/0002-9343(82)90082-1
Expert Opinion
1317822* | 220719 Extrapolation of pharmacological properties in man and veterinary species. Some material employed in collating the data displayed here was taken from veterinary product datasheets or extrapolated from pharmacology texts.