Zolazepam-Tiletamine
Avoid Use
Limited work with these agents in rabbits has suggested that Acute Kidney Injury (azotemia, proteinuria and the presence of tubular casts) is associaced with intramuscular tiletamine administration. therefore uae is not recommended.
Brammer, D., Doerning, B., Chrisp, C., Rush, H., 1991. Anesthetic and nephrotoxic effects of Telazol in New Zealand white rabbits. Laboratory animal science.
Doerning, B.J., Brammer, D.W., Chrisp, C.E., Rush, H.G., 1992. Nephrotoxicity of tiletamine in New Zealand white rabbits. Lab Anim Sci 42, 267–269.
Karasu, A., Altug, N., Aslan, L., Bakir, B., Yuksek, N., 2018. Evaluation of the anesthetic effects of xylazine-ketamine, xylazine-tiletamine-zolazepam and tiletamine-zolazepam using clinical and laboratory parameters in rabbits. Medycyna Weterynaryjna 74, 646–652. https://doi.org/10.21521/mw.6119
Topal, A., Gul Satar, N.Y., Ates, O., Uckan, E.M., Yavas, O., Cangul, I.T., 2023. Comparison of the Effects of Ketamine-Diazepam, Tiletamine-Zolazepam and Propofol Infusion Anesthesia in Rabbits. Kafkas Univ Vet Fak Derg. https://doi.org/10.9775/kvfd.2022.28744
Willeford, B.V., Davison, S.E., Meyer, R.E., 2023. Chapter 4 - Injectable anesthetics, in: Dyson, M.C., Jirkof, P., Lofgren, J., Nunamaker, E.A., Pang, D. (Eds.), Anesthesia and Analgesia in Laboratory Animals (Third Edition), American College of Laboratory Animal Medicine. Academic Press, San Diego, pp. 47–86. https://doi.org/10.1016/B978-0-12-822215-7.00028-7