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Gabapentin

Grade

Multimodal Analgesia

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Therapeutics

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Evidence

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  1. Anfuso, C.D., Olivieri, M., Fidilio, A., Lupo, G., Rusciano, D., Pezzino, S., Gagliano, C., Drago, F., Bucolo, C., 2017. Gabapentin Attenuates Ocular Inflammation: In vitro and In vivo Studies. Front Pharmacol 8, 173. https://doi.org/10.3389/fphar.2017.00173

  2. Berg, K., 2018. Therapeutic Review: GABAPENTIN. Journal of Exotic Pet Medicine 27, 78–81. https://doi.org/10.1053/j.jepm.2018.07.002

  3. Burton, M., Conway, R., Mishkin, N., Mama, K., Knych, H., Kendall, L., Sadar, M.J., 2023. Pharmacokinetics of gabapentin after single, oral administration in domestic rabbits (Oryctolagus cuniculus). Journal of Exotic Pet Medicine 45, 1–5. https://doi.org/10.1053/j.jepm.2023.02.001

  4. Cheng, J.-K., Chiou, L.-C., 2006. Mechanisms of the Antinociceptive Action of Gabapentin. J Pharmacol Sci 100, 471–486. https://doi.org/10.1254/jphs.CR0050020

  5. Conway, R.E., Burton, M., Mama, K., Rao, S., Kendall, L.V., Desmarchelier, M., Sadar, M.J., 2023. Behavioral and Physiologic Effects of a Single Dose of Oral Gabapentin in Rabbits (Oryctolagus cuniculus). Top Companion Anim Med 53–54, 100779. https://doi.org/10.1016/j.tcam.2023.100779

  6. Kale, A., Börcek, A.Ö., Emmez, H., Yildirim, Z., Durdağ, E., Lortlar, N., Kurt, G., Doğulu, F., Kılıç, N., 2011. Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits. J Neurosurg Spine 15, 228–237. https://doi.org/10.3171/2011.4.SPINE10583

  7. Korkmaz, M., Saritas, T.B., Sevimli, A., Saritas, Z.K., Elitok, B., 2015. The effect of gabapentin and pregabalin on intestinal incision wound healing in rabbits. Vet World 8, 279–283. https://doi.org/10.14202/vetworld.2015.279-283

  8. Petrere, J.A., Anderson, J.A., 1994. Developmental Toxicity Studies in Mice, Rats, and Rabbits with the Anticonvulsant Gabapentin. Fundamental and Applied Toxicology 23, 585–589. https://doi.org/10.1006/faat.1994.1144

  9. Pietrzak, B., Czarnecka, E., 2006a. Effect of the administration of tiagabine and gabapentin on rabbit electroencephalogram activity. J Pharm Pharmacol 58, 1367–1372. https://doi.org/10.1211/jpp.58.10.0010

  10. Pietrzak, B., Czarnecka, E., 2006b. The effect of combined administration of ethanol and gabapentin on rabbit electroencephalographic activity. Basic Clin Pharmacol Toxicol 99, 383–390. https://doi.org/10.1111/j.1742-7843.2006.pto_518.x

  11. Piyapolrungroj, N., Li, C., Bockbrader, H., Liu, G., Fleisher, D., 2001. Mucosal uptake of gabapentin (neurontin) vs. pregabalin in the small intestine. Pharm Res 18, 1126–1130. https://doi.org/10.1023/a:1010970809090

Monograph Details

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