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Ciprofloxacin

Grade

Sensitive Infections

See through space
Therapeutics

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Evidence

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  1. Aramayona, J.J., Mora, J., Fraile, L.J., García, M.A., Abadía, A.R., Bregante, M.A., 1996. Penetration of enrofloxacin and ciprofloxacin into breast milk, and pharmacokinetics of the drugs in lactating rabbits and neonatal offspring. Am J Vet Res 57, 547–553.

  2. Bashir, S., Jamshaid, M., Ahmad, B., Iqbal, J., 2008. Pharmacokinetics of ciprofloxacin in normal rabbits and changes observed in induced dehydrated state. Pak J Pharm Sci 21, 225–229.

  3. Behrens-Baumann, W., 1996. Absorption of topically administered ciprofloxacin, ofloxacin and gentamicin in the inflamed rabbit eye. Ophthalmologica 210, 119–122. https://doi.org/10.1159/000310687

  4. Elmas, M., Yazar, E., Baş, A.L., Traş, B., Bayezit, M., Yapar, K., 2002. Comparative pharmacokinetics of enrofloxacin and tissue concentrations of parent drug and ciprofloxacin after intramuscular administrations of free and liposome-encapsulated enrofloxacin in rabbits. J Vet Med B Infect Dis Vet Public Health 49, 507–512. https://doi.org/10.1046/j.1439-0450.2002.00603.x

  5. Fraile, L.J., Martinez, C., Aramayona, J.J., Abadía, A.R., Bregante, M.A., García, M.A., 1997. Limited capacity of neonatal rabbits to eliminate enrofloxacin and ciprofloxacin. Vet Q 19, 162–167. https://doi.org/10.1080/01652176.1997.9694764

  6. Green, L.C., Callegan, M.C., Engel, L.S., Shimomura, Y., Jasheway, D.W., O’Callaghan, R.J., Hill, J.M., 1996. Pharmacokinetics of topically applied ciprofloxacin in rabbit tears. Jpn J Ophthalmol 40, 123–126.

  7. Hanan, M.S., Riad, E.M., el-Khouly, N.A., 2000. Antibacterial efficacy and pharmacokinetic studies of ciprofloxacin on Pasteurella multocida infected rabbits. Dtsch Tierarztl Wochenschr 107, 151–155.

  8. Klaus, R., Jin, C., Maier-Salamon, A., Jäger, W., Knopf, C., Zeitlinger, M., Richter-Müksch, S., Schmidl, D., Schmetterer, L., Garhöfer, G., 2016. An Exploratory Microdialysis Study to Assess the Ocular Pharmacokinetics of Ciprofloxacin Eye Drops in Rabbits. J Ocul Pharmacol Ther 32, 390–395. https://doi.org/10.1089/jop.2015.0131

  9. Marchese, A.L., Slana, V.S., Holmes, E.W., Jay, W.M., 1993. Toxicity and pharmacokinetics of ciprofloxacin. J Ocul Pharmacol 9, 69–76. https://doi.org/10.1089/jop.1993.9.69

  10. Ramon, J., Dautrey, S., Farinoti, R., Carbon, C., Rubinstein, E., 1996. Excretion of ciprofloxacin into the large bowel of the rabbit. Antimicrob Agents Chemother 40, 11–13. https://doi.org/10.1128/AAC.40.1.11

  11. Ramon, J., Dautrey, S., Farinoti, R., Carbon, C., Rubinstein, E., 1994. Intestinal elimination of ciprofloxacin in rabbits. Antimicrob Agents Chemother 38, 757–760. https://doi.org/10.1128/AAC.38.4.757

  12. Rootman, D.S., Savage, P., Hasany, S.M., Chisholm, L., Basu, P.K., 1992. Toxicity and pharmacokinetics of intravitreally injected ciprofloxacin in rabbit eyes. Can J Ophthalmol 27, 277–282.

  13. Stevens, S.X., Fouraker, B.D., Jensen, H.G., 1991. Intraocular safety of ciprofloxacin. Arch Ophthalmol 109, 1737–1743. https://doi.org/10.1001/archopht.1991.01080120121040

Monograph Details

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