Aglepristone
Pregnancy Termination
Early induction days 5 and 6
Mid-term induction days 15 and 16
Therapeutics
Evidence Base
Rabbit Aglepristone Evidence Base
Özalp, G., Çalışkan, Ç., Seyrek-İntaş, K., Wehrend, A., 2008. Effects of the Progesterone Receptor Antagonist Aglepristone on Implantation Administered on Days 6 and 7 after Mating in Rabbits: Effects of the Progesterone Receptor Antagonist Aglepristone. Reproduction in Domestic Animals 45, 505–508. https://doi.org/10.1111/j.1439-0531.2008.01282.x
Özalp, G.R., Seyrek-İntaş, K., Çalışkan, Ç., Wehrend, A., 2008. Mid-gestation pregnancy termination in rabbits by the progesterone antagonist aglepristone. Theriogenology 69, 1056–1060. https://doi.org/10.1016/j.theriogenology.2008.01.016
Özalp, G.R., Temizel, E.M., Özocak-Batmaz, E., 2013. Clinical, ultrasonography and haematology of aglepristone-induced mid-gestation pregnancy terminations in rabbits. J. S. Afr. Vet. Assoc. 84. https://doi.org/10.4102/jsava.v84i1.998
Parillo, F., Dall’Aglio, C., Brecchia, G., Maranesi, M., Polisca, A., Boiti, C., Zerani, M., 2013. Aglepristone (RU534) effects on luteal function of pseudopregnant rabbits: Steroid receptors, enzymatic activities, and hormone productions in corpus luteum and uterus. Animal Reproduction Science 138, 118–132. https://doi.org/10.1016/j.anireprosci.2013.02.001
Expert Opinion
1317822* | 221003 Extrapolation of pharmacological properties in man and veterinary species. Some material employed in collating the data displayed here was taken from veterinary product datasheets or extrapolated from pharmacology texts.
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