top of page

Azithromycin

Grade

Treponema cuniculi (Oral Protocol)

Therapeutics

Evidence

  1. Asano, N., Wiseman, J.M., Tsuji, F., Kawazu, K., 2017. Limited Azithromycin Localization to Rabbit Meibomian Glands Revealed by LC-MS-Based Bioanalysis and DESI Imaging. Biol Pharm Bull 40, 1586–1589. https://doi.org/10.1248/bpb.b17-00288

  2. Cam, D., Saatci, A.O., Micili, S.C., Ergur, B.U., Karabag, R.Y., Durak, I., Berk, A.T., 2016. The Effect of Intravitreal Azithromycin on the Albino Newborn Rabbit Retina. Open Ophthalmol J 10, 12–16. https://doi.org/10.2174/1874364101610010012

  3. Cárceles, C.M., Fernández-Varón, E., Marı´n, P., Escudero, E., 2007. Tissue disposition of azithromycin after intravenous and intramuscular administration to rabbits. The Veterinary Journal 174, 154–159. https://doi.org/10.1016/j.tvjl.2006.05.022

  4. Escudero, E., Fernández-Varón, E., Marín, P., Espuny, A., Nájera, M.D., Cárceles, C.M., 2006. Pharmacokinetics and tissue tolerance of azithromycin after intramuscular administration to rabbits. Research in Veterinary Science 81, 366–372. https://doi.org/10.1016/j.rvsc.2006.01.006

  5. Giacani, L., Bernstein, L.R., Haynes, A.M., Godornes, B.C., Ciccarese, G., Drago, F., Parodi, A., Valdevit, S., Anselmi, L., Tomasini, C.F., Baca, A.M., 2019. Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws. PLoS Negl Trop Dis 13, e0007076. https://doi.org/10.1371/journal.pntd.0007076

  6. Ikemoto, K., Kobayashi, S., Haranosono, Y., Kozai, S., Wada, T., Tokushige, H., Kawamura, A., 2020. Contribution of anti-inflammatory and anti-virulence effects of azithromycin in the treatment of experimental Staphylococcus aureus keratitis. BMC Ophthalmol 20, 89. https://doi.org/10.1186/s12886-020-01358-4

  7. Pereira, L.E., Katz, S.S., Sun, Y., Mills, P., Taylor, W., Atkins, P., Thurlow, C.M., Chi, K.-H., Danavall, D., Cook, N., Ahmed, T., Debra, A., Philip, S., Cohen, S., Workowski, K.A., Kersh, E., Fakile, Y., Chen, C.Y., Pillay, A., 2020. Successful isolation of Treponema pallidum strains from patients’ cryopreserved ulcer exudate using the rabbit model. PLoS One 15, e0227769. https://doi.org/10.1371/journal.pone.0227769

  8. Sakai, T., Shinno, K., Kurata, M., Kawamura, A., 2019. Pharmacokinetics of Azithromycin, Levofloxacin, and Ofloxacin in Rabbit Extraocular Tissues After Ophthalmic Administration. Ophthalmol Ther 8, 511–517. https://doi.org/10.1007/s40123-019-00205-0

  9. You, L., Qian, J., Wu, X., Sun, X., Su, M., Di, B., Du, Y., Mao, B., 2013. Propagation of error in ocular pharmacokinetic parameters estimate of azithromycin in rabbits. J Pharm Sci 102, 2371–2379. https://doi.org/10.1002/jps.23557

Monograph Details

bottom of page