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Atipamezole

Grade

Dexmedetomidine Reversal

Therapeutics


  • Intranasal administration of atipamezole will effectively antagonise intranasally administered dexmedetomidine in many species.


Evidence

  1. Johnson, J.G., Chinnadurai, S.K., 2022. Drug Delivery and Safety Considerations. Veterinary Clinics of North America: Exotic Animal Practice, Sedation and Anesthesia of Zoological Companion Animals 25, 1–11. https://doi.org/10.1016/j.cvex.2021.08.014

  2. Khelik, I., Johnson, J.G., McCool, E., Fentiman, K., Soler, E., Tully, T., Brandão, J., 2023. Aberrant conjunctival overgrowth with corneal adhesions in two pet rabbits (Oryctolagus cuniculus). Journal of Exotic Pet Medicine 46, 32–37. https://doi.org/10.1053/j.jepm.2023.04.001

  3. Pelchat, J., Desprez, I., Beaufrère, H., Beazley, S.G., Duke-Novakovski, T., 2023. Comparison between mainstream (Capnostat 5) and a low-flow sidestream capnometer (Capnostream) in mechanically ventilated, sevoflurane-anesthetized rabbits using a Bain coaxial delivery system. Veterinary Anaesthesia and Analgesia 50, 81–90. https://doi.org/10.1016/j.vaa.2022.11.004

  4. Roeder, M., Boscan, P., Rao, S., Proença, L., Guerrera, W., Grayck, M., Gish, M., Sullivan, M.N., Sadar, M.J., 2023. Use of maropitant for pain management in domestic rabbits (Oryctolagus cuniculus) undergoing elective orchiectomy or ovariohysterectomy. Journal of Exotic Pet Medicine 47, 14–20. https://doi.org/10.1053/j.jepm.2023.07.001

  5. Takizawa, H., Bacmeister, C., Brandão, J., 2023. Shope fibroma in the scrotum of a domestic rabbit (Oryctolagus cuniculus). Journal of Exotic Pet Medicine 46, 5–6. https://doi.org/10.1053/j.jepm.2023.03.004

  6. The efficacy of intranasal administration of dexmedetomidine, ketamine and morphine combination to rabbit | International Journal of Development Research (IJDR), 2016. . International Journal of Development Research Vol. 06, pp.8634-8636,.


Expert Opinion

  1. 1317822  Extrapolation of pharmacological properties in man and veterinary species. Some material employed in collating the data displayed here was taken from veterinary product datasheets or extrapolated from pharmacology texts.


Monograph Details

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